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Cordycepin attenuates caerulein-stimulated degenerative histological features of pancreatic injury, such as augmented inflammatory cell (neutrophil) infiltration, and reduced edema, acinar cell vacuolization, and serum amylase and lipase levels

Bioavailable supplementation may support mitochondrial function, liver detoxification, and help reduce post-exertional malaise (PEM)

Cysteine-rich foods include animal protein, whole grains like wheat and quinoa, and soybeans.2 NAC could potentially benefit people with BD by decreasing oxidative stress levelsthrough increased production of glutathione, an antioxidantand altering neurotransmitter levels for antidepressant effects.2,7 Some studies have supported the antidepressant effects of NAC in participants with BD, while others have not found any positive results.2,13,16,20 One recent double-blind randomized controlled trial including 67 individuals with BD and depression found that participants with high levels of the inflammatory marker C-reactive protein who took 1.8 g of NAC daily for 12 weeks had significantly reduced symptoms of depression and reduced levels of C-reactive protein compared with those receiving a placebo.2,16 While evidence for the benefits of antioxidant supplements is preliminary, Velasco-Popov recommends that people with BD include foods high in CoQ10 and L-cysteine: These antioxidants may play a supportive role in helping manage symptoms of depression in patients with BD