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By improving vascular perfusion within granulomas, HDT can increase the local concentration of antimicrobials, promote tissue repair, and enhance the clearance of latent mycobacteria by immune cells

Methionine is easily converted to S-adenosylmethionine (SAM), the primary methyl donor in various methylation reactions, including DNA methylation and neurotransmitter synthesis

Although RPM did not attenuate the systemic immune activation induced by heat-stress challenge, the study demonstrated that RPM had a protective effect on the mammary gland (Pate et al., 2021)