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Description

Previously it has been demonstrated that Ac is toxic to the pulmonary endothelial cells and bronchial epithelial cells at concentrations ranging from 25 M = 1.4 g/mL to 100 M = 5.6 g/mL ( Based on these observations we hypothesize that Su serves as a marker of increased BU conjugation with glutathione (GSH) and higher CYP2C9 activity and, thus representing a population with increased CY activation