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Next, we used proteomics results to stratify COPD patients into 3 subgroups (Table 3): subtype I were mainly COPD without other respiratory diseases (simplex COPD, n = 19), subtype II largely for COPD co-existing with bronchiectasis (COPD-BE, n = 9), and subtype III focused on COPD co-existing with metabolic syndrome (COPD-MD, n = 12)

Normal psychiatric, hepatic, respiratory and psychomotor status was seen in 88, 84, 84 and 64% of episodes, respectively, at study endpoint, compared with 71, 75, 61 and 64% of episodes at baseline [11]

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