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In patients with SS, CXCL10 + CCL19 + fibroblasts may participate in the development of inflammatory lesions by providing signals such as IFN, IL-1, and TNF, which could exacerbate SG lymphocytic infiltration and favor the resemblance of TLS (31, 38, 142)

It is also known to lower triglycerides and uric acid and to influence the microbiotas fecal butyrate-producing bacteria ( Lachnospiraceae and Lachnoclostridium )

Dietary interventions for autism spectrum disorder: New perspectives from the gut-brain axis

Previous studies at a dosage of up to 10 mg/kg caffeine showed no anxiolytic or anxiogenic effects in an open-field test and an elevated plus-maze test (Bhattacharya et al