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Circulation 124 , 465476 (2011)

Imitrex Injection belongs to a class of medications called selective serotonin receptor agonists

This intermediate is nucleophilically attacked by the active site tyrosine residue (Tyr114) to form a covalent vinylether adduct, leading to inhibition of the enzyme (Figure 6A) (Yadav et al., 2019)

In addition, GPx2 expression appears to be under the control of a number of transcription factors that are involved in the regulation of cell proliferation and differentiation, such as p63 isoforms, -catenin, Nkx3.1, and retinoic acid (Chu et al., 1999