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Description

Neal, B., Perkovic, V

10.1016/j.exger.2014.01.026 32 DesbatsM

To open, tear outer wrap at the notch and remove solution bag

We analyzed the presence and clearance of TAM and its metabolites (N-desmethyl-tamoxifen, 4-hydroxytamoxifen and endoxifen) in brain and serum of mice by liquid chromatographic-high resolution-tandem mass spectrometry (LC-HR-MS/MS) and assessed optimal injection protocols by quantitative RT-PCR of several floxed target genes ( p2ry1 , gria1, gabbr1 and Rosa26-tdTomato locus )