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7.2 Characteristics of alginic acid and application of nano-carriers ALG is a naturally occurring polysaccharide rich in hydroxyl and carboxyl groups, enabling hydrogen bonding, gel formation, mucoadhesion, and enhanced transdermal penetration (198)

A key approach involves inhibiting enzymes like ACSL4, which incorporates polyunsaturated fatty acids into membranes, a critical step for ferroptosis ( 4.3 Anti-inflammatory and multitarget approaches Neuroinflammation amplifies ferroptosis via DAMPs and cytokines, creating a vicious cycle of damage ( 4.4 Innovative therapeutic platforms Emerging therapeutic platforms aim to overcome the limitations of small molecules through enhanced targeting and delivery

Mixing different peptides can lead to unknown chemical reactions, pH changes, and potential degradation of both compounds

Trx1, a 105-amino-acid redox protein with a molecular mass of 12 kDa, is an important component of the Trx system and is mainly localized in the cytoplasm and nucleus (10,18)