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Risk factors that should prompt consideration of B12 deficiency include advancing age (reduced stomach acid production), strict vegan or vegetarian diets, pernicious anaemia, gastrointestinal surgery (particularly gastric bypass or ileal resection), long-term use of certain medications (metformin, proton pump inhibitors, H2-receptor antagonists), nitrous oxide exposure (including recreational use), and conditions affecting the gut such as Crohn's disease or coeliac disease

They are often recommended for individuals who struggle to absorb B12 from food or supplements, such as those with certain medical conditions or dietary restrictions

This information is not individual medical advice and does not substitute for the advice of your health care professional

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