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205 Mitonuclear feedback is achieved through bidirectional communication: anterograde signaling, where information flows from the nucleus to the mitochondria, and retrograde signaling (RTG), where the mitochondria transmit signals to the nucleus in response to mitochondrial dysfunction

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Increases mobility in peripheral artery disease Occlusive peripheral arterial disease is caused by atherosclerosis, which is a buildup of fatty deposits in the artery